Search results for "Extracorporeal Shock Waves COPD"

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Extracorporeal Shock Waves Increase Markers of Cellular Proliferation in Bronchial Epithelium and in Primary Bronchial Fibroblasts of COPD Patients

2020

Chronic obstructive pulmonary disease (COPD) is due to structural changes and narrowing of small airways and parenchymal destruction (loss of the alveolar attachment as a result of pulmonary emphysema), which all lead to airflow limitation. Extracorporeal shock waves (ESW) increase cell proliferation and differentiation of connective tissue fibroblasts. To date no studies are available on ESW treatment of human bronchial fibroblasts and epithelial cells from COPD and control subjects. We obtained primary bronchial fibroblasts from bronchial biopsies of 3 patients with mild/moderate COPD and 3 control smokers with normal lung function. 16HBE cells were also studied. Cells were treated with a…

Extracorporeal Shockwave TherapyMalePathologyPulmonary Disease Chronic Obstructive0302 clinical medicineMedicine0303 health sciencesCOPDSmokersbiologyCell DifferentiationMiddle AgedProto-Oncogene Proteins c-kitmedicine.anatomical_structurepsychological phenomena and processesResearch ArticlePulmonary and Respiratory MedicineExtracorporeal Shock Waves COPDCell typemedicine.medical_specialtyArticle SubjectPrimary Cell CultureeducationConnective tissueBronchibehavioral disciplines and activitiesCollagen Type ICell LineTransforming Growth Factor beta1Diseases of the respiratory system03 medical and health sciencesProliferating Cell Nuclear AntigenParenchymaHumansCD90RNA MessengerAgedCell Proliferation030304 developmental biologyRC705-779business.industryCD117Cell growthTranscription Factor RelAEpithelial CellsFibroblastsmedicine.diseaserespiratory tract diseasesProliferating cell nuclear antigen030228 respiratory systemCase-Control Studiesbiology.proteinbusiness
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